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AssigneeDongwha Pharmaceutical Co., Ltd.
InventorsHong-Suk SUH, Jin Soo Lee, Pan-Soo Kim, Yun-Ha Hwang, Jei Man Ryu, Yong-Ho Chung, Eun-Joo Kim, Do-Hui Kim, Yong-Youp Park
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This invention relates to a pharmaceutical composition containing 4-[(4-thiazolyl)phenoxyl]alkoxy-benzamidine derivatives expressed by the following formula 1 for the prophylaxis and treatment of osteoporosis and more particularly, to the use of 4-{5-[4-(5-isoproply-2-methyl-1,3-thiazol-4-yl)phenoxyl]pentoxy}-benzamidine or N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxyl]pentoxy}-benzamidine expressed by the following formula 1 as a pharmaceutical composition for the prophylaxis and treatment of osteoporosis.
A method for the prophylaxis of osteoporosis in a subject, the method comprising administering a composition comprising the compound of following formula 1 or a salt thereof to the subject in an amount effective to inhibit osteoclast activity and to stimulate osteoblast activity:
Dependencies are inferred from the claim text.