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US 2010/0160393 A1Published application
Crystal form of epothilone b and use in pharmaceutical compositions
AssigneeNovartis AG
InventorsErnst Küsters, Michael Mutz, Frank Stowasser
Life of this patent
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Abstract
The invention relates to new crystal forms of epothilone B.
Claims6
A crystal form of epothilone B having the reference modification C, which is characterised by the X-ray diffraction diagram reproduced in the form of a table.
- 2θ
- Intensity
- 17.5
- strong
- 18.3
- strong
3 more elements
A crystal form of epothilone B having the reference modification C, which is characterised by the X-ray diffraction diagram reproduced in the form of a table.
- 2θ
- Intensity
- 6.5
- medium
- 11.8
- medium
- 13.1
- medium
- 17.5
- strong
- 18.3
- strong
- 19.6
- medium
- 21.6
- medium
13 more elements
A crystal form of epothilone B having the reference modification C, which is characterised by the Structural data when crystallized from isopropylacetate
- A (Å)
- 10.3302(2)
- b(Å)
- 12.0132(14)
- c (Å)
- 27.070(4)
- Beta (°)
- —
- Cell volume (Å3)
- 3359.4(7)
- Z
- 4
- Density (g/cm3)
- 1.206
- Solvent:EPO906
- 1:1
13 more elements
(canceled)
Dependencies are inferred from the claim text.