US 2010/0150414 A1 · GENE EXPRESSION IMAGE CONSTRUCTING METHOD AND GENE EXPRESSION IMAGE CONSTRUCTING SYSTEM

Abstract

The present invention aims to provide a gene expression image constructing method and a gene expression image constructing system being able to three-dimensionally show expression patterns of a vastly larger number of genes (specifically, about 30,000 genes). In the present invention, a sample is cut, images of sections of the cut sample are picked up and a stereoscopic image of sample, which is a three-dimensional image of the sample, is constructed based on a plurality of picked-up section images, the amount of expression of genes present in the sample is measured based on a plurality of slices prepared when the sample is cut, and a gene expression image in which an expression state of genes present in the sample and a stereoscopic image of sample are associated with each other is constructed based on a predetermined image reconstruction technique from the constructed stereoscopic image of sample and the measured amount of expression.

Claims12

Dependent claims

A gene expression image constructing method for constructing a gene expression image in which an expression state of genes present in a sample and a stereoscopic image of the sample are associated with each other, the method comprising a cutting step of cutting the sample;

and a sample stereoscopic image construction step of picking up images of sections of the sample cut at the cutting step and constructing the stereoscopic image of the sample which is a three-dimensional image of the sample, based on a plurality of picked-up section images, the method further comprising:
an expression amount measurement step of measuring an amount of expression of the genes present in the sample based on a plurality of slices prepared when the sample is cut at the cutting step;
and
a gene expression image construction step of constructing the gene expression image based on a predetermined image reconstruction technique from the stereoscopic image of the sample constructed at the sample stereoscopic image construction step and the amount of expression measured at the expression amount measurement step.

1 more element

A gene expression image constructing system that constructs a gene expression image in which an expression state of genes present in a sample and a stereoscopic image of the sample are associated with each other, the system comprising a cutting unit that cuts the sample;

and a sample stereoscopic image construction unit that picks up images of sections of the sample cut by the cutting unit and constructs the stereoscopic image of the sample which is a three-dimensional image of the sample, based on a plurality of picked-up section images, the system further comprising:
an expression amount measurement unit that measures an amount of expression of the genes present in the sample based on a plurality of slices prepared when the sample is cut by the cutting unit;
and
a gene expression image construction unit that constructs the gene expression image based on a predetermined image reconstruction technique from the stereoscopic image of the sample constructed by the sample stereoscopic image construction unit and the amount of expression measured by the expression amount measurement unit.

1 more element

Dependencies are inferred from the claim text.

Gene expression image constructing method and gene expression image constructing system

Life of this patent

Gene expression image constructing method and gene expression image constructing system

Life of this patent

Abstract

Claims12