Microarray reader based on evanescent wave detection and method of reading a microarray
AssigneeHoneywell International Inc.
InventorsYuan Zheng, Leon Xu, Zhenhong Sun
Life of this patent
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Abstract
A microarray reader (100) comprises a light source (102), beam shaping elements (104) positioned near the light source (102), a moving stage (124) supporting one or more of the light source (102) and beam shaping elements (104), an optical substrate (112) supporting an immobilized microarray, a reaction chamber (116) in contact with the optical substrate (112) and encapsulating buffer solution, a heating/cooling component (118) in contact with the reaction chamber (116), a synchronization circuit, an optical filter (108) and an imaging sensor (106) positioned near the optical filter (108).
Claims9
A microarray reader, comprising:
- a light source;
- beam shaping elements, positioned near the light source;
- a moving stage, supporting one or more of the light source and beam shaping elements;
- an optical substrate, supporting an immobilized microarray;
- a reaction chamber, in contact with the optical substrate and encapsulating a buffer solution;
- a heating/cooling component, in contact with the reaction chamber;
- a synchronization circuit;
- an optical filter;
- and
- an imaging sensor, positioned near the optical filter.
A method for reading a microarray, comprising:
- initializing a microarray reader system;
- initiating a temperature control circuit;
- monitoring a real-time temperature control;
- capturing microarray images;
- and
- analyzing the images.
Dependencies are inferred from the claim text.