Method, apparatus, and kit for onychomycosis treatment

A device for the treatment of onychomycosis comprising:

• at least one active electrode for facilitating delivery of an anti-fungal agent into an onychomycosis infected region of at least one digit, by application of an electrical current to the region;
• at least one counter electrode facilitating closing of electrical circuit with the at least one active electrode;
• at least one power source for providing a current and voltage, connected through a conductive media to the active and counter electrodes;
• and
• at least one base member supporting the at least one active electrode, the at least one counter electrode, and the at least one power source,
• wherein the device has a first flat position and a second curved position conforming to the curvature of the digit, and
• wherein the at least one active electrode is adapted to be disposed on the onychomycosis infected region of the at least one digit and the at least one counter electrode is adapted to be disposed on a non-infected region of the at least one digit in both the first position and the second position.

A device for the treatment of onychomycosis comprising:

• at least one active electrode for facilitating delivery of an anti-fungal agent into an onychomycosis infected region of at least one digit, by application of an electrical current to the region;
• at least one counter electrode facilitating closing of electrical circuit with the at least one active electrode;
• at least one power source for providing a current and voltage, connected through a conductive media to the active and counter electrodes;
• and
• at least one base member supporting the at least one active electrode, the at least one counter electrode, and the at least one power source,
• wherein the at least one active electrode is adapted to be disposed on the onychomycosis infected region of the at least one digit, wherein the at least one anti-fungal agent is a terbinafine compound in a formulation, wherein the formulation is electrically conductive and comprises the terbinafine compound solubilized in water, terbinafine cations and a gelling agent.

A device for the treatment of onychomycosis comprising at least one flexible wearable patch conformable to the contour of at least a non-nail portion of at least one digit and at least part of the nail portion of the at least one digit, the flexible wearable patch comprising:

• at least one active electrode for facilitating delivery of an anti-fungal agent into a region of the at least part of the nail portion of the at least one digit infected with onychomycosis, by application of an electrical current to the region;
• at least one counter electrode facilitating closing of electrical circuit with the at least one active electrode;
• a composition disposed on the at least one active electrode;
• at least one power source for providing a current and voltage, connected through a conductive media to the active and counter electrodes;
• and
• a base member supporting the at least one active electrode, the at least one counter electrode, and the at least one power source, wherein the base member is in a folded configuration on the digit, so that the at least one active electrode is adapted to be disposed on the region of the digit infected with onychomycosis and wherein the at least one counter electrode is adapted to be disposed on a non-infected region of the digit.

A device for the treatment of onychomycosis comprising:

• at least one active electrode for facilitating delivery of an anti-fungal agent into an onychomycosis infected region of at least one digit, by application of an electrical current to the region;
• at least one counter electrode facilitating closing of electrical circuit with the at least one active electrode;
• at least one power source for providing a current and voltage, connected through a conductive media to the active and counter electrodes;
• and
• at least one base member comprising a midline portion, a left lateral portion and a right lateral portion, wherein the at least one base member supports the at least one active electrode, the at least one counter electrode, and the at least one power source,
• wherein the at least one active electrode is supported on the midline portion, and
• wherein the at least one active electrode is adapted to be disposed on the onychomycosis infected region of the at least one digit, the at least one counter electrode is adapted to be disposed on a non-infected region of the at least one digit, and the left lateral portion and the right lateral portion are adapted to wrap around the at least one digit.