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US 2010/0145080 A1Published application
Purification of taxanes
AssigneePhyton Holdings, LLC
InventorsJames H. Johnson, T.G. Sambandam, Barry J. Hand, Christopher D. Howe, Roland R. Franke, Brian A. Bucher, John S. Juchum, Rex T. Gallagher, Marc A. Plante, Edward M. Desimone, III, Dong S. Yang
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Abstract
Disclosed is a method of crystallizing a taxane comprising combining the taxane and methylene chloride to obtain a solution and adding an anti-solvent to the solution to obtain a crystalline taxane, wherein the anti-solvent is selected from the group consisting of hexane and heptane.
Claims6
A method of crystallizing a taxane comprising:
- (a) combining the taxane and methylene chloride to obtain a solution;
- and
- (b) adding an anti-solvent to the solution to obtain a crystalline taxane,
- wherein the anti-solvent is selected from the group consisting of hexane and heptane.
1 more element
Dependencies are inferred from the claim text.