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US 2010/0145064 A1Published application
Method for the preparation of zolmitriptan
OwnerMichal Voslar, Monika Zatopkova +2inventors
InventorsMichal Voslar, Monika Zatopkova, Hana Petrickova, Lucie Tisovska
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Abstract
A method for the preparation of zolmitriptan or its pharmaceutically acceptable salts, comprising isolation of a crystalline salt of zolmitriptan, its optional re-purification and conversion to the substance of formula (III). Zolmitriptan hydrochloride in the crystalline state.
Claims9
A method for the preparation of (S)-4-[{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl]-2-oxazolidinone (zolmitriptan) of formula III
- or its pharmaceutically acceptable salts, prepared by isolation of a crystalline salt of zolmitriptan re-purification, and conversion converted into the substance of formula III.
A crystalline zolmitriptan hydrochloride.
Dependencies are inferred from the claim text.