Use of dicalcium phosphate anhydride powder
AssigneeChemische Fabrik Budenheim KG
InventorsErhard Fischer, Gerhard Scheuer, Jurgen Meven, Stefan Mallmann, Silke John
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Abstract
Dicalcium phosphate anhydride powder of which at least 50% by weight is of a grain size of between 45 and 150 μm, a maximum of 50% by weight is of a grain size of <45 μm and a maximum of 5% by weight is of a grain size >150 μm and which has a bulk density of between 1000 and 1500 g/l and a specific surface area of <5 m2/g is used for direct tabletting or capsule filling of pharmaceutical preparations.
Claims7
A method of using a dicalcium phosphate anhydride powder comprising:
- providing a dicalcium phosphate anhydride powder having a bulk weight of between 1000 and 1500 g/l, wherein at least 50% by weight of said powder is of a grain size of between 45 and 150 μm, a maximum of 50% by weight of said powder is of a grain size of <45 μm and a maximum of 5% by weight of said powder is of a grain size of >150 μm, wherein said powder has a specific surface area of <5 m2/g;
- and
- direct tabletting at least one pharmaceutical product with said dicalcium phosphate anhydride powder.
A method of using a dicalcium phosphate anhydride powder comprising:
- providing a dicalcium phosphate anhydride powder having a bulk weight of between 1000 and 1500 g/l, wherein at least 50% by weight of said powder is of a grain size of between 45 and 150 μm, a maximum of 50% by weight of said powder is of a grain size of <45 μm, and a maximum of 5% by weight of said powder is of a grain size of >150 μm;
- wherein said powder has a specific surface area of <5 m2/g;
- and
- capsule filling at least one pharmaceutical product with said dicalcium phosphate anhydride powder.
The method as claimed in claim 4 wherein said dicalcium phosphate anhydride powder comprises a bulk weight of between 1200 and 1400 g/l.
A method of using a dicalcium phosphate anhydride powder comprising:
- providing a dicalcium phosphate anhydride powder by direct precipitation, said powder having a bulk weight of between 1000 and 1500 g/l;
- wherein at least 50% by weight of said powder is of a grain size of between 45 and 150 μm, a maximum of 50% by weight of said powder is of a grain size of <45 μm, and a maximum of 5% by weight of said powder is of a grain size >150 μm, wherein said powder has a specific surface area of <5 m2/g;
- and
- direct tabletting or capsule filling at least one pharmaceutical product with said dicalcium phosphate anhydride powder.
A tabletted pharmaceutical product comprising dicalcium phosphate anhydride powder, said powder having a bulk weight of between 1000 and 1500 g/l;
- wherein at least 50% by weight of said powder is of a grain size of between 45 and 150 μm, a maximum of 50% by weight of said powder is of a grain size of <45 μm, and a maximum of 5% by weight of said powder is of a grain size >150 μm, wherein said powder has a specific surface area of <5 m2/g.
A pharmaceutical product comprising a capsule filled with dicalcium phosphate anhydride powder, said powder having a bulk weight of between 1000 and 1500 g/l;
- wherein at least 50% by weight of said powder is of a grain size of between 45 and 150 μm, a maximum of 50% by weight of said powder is of a grain size of <45 μm, and a maximum of 5% by weight of said powder is of a grain size >150 μm, wherein said powder has a specific surface area of <5 m2/g.
Dependencies are inferred from the claim text.