Topically applicable compositions for the treatment of keratinization disorders
AssigneeGalderma Research & Development, Biot, France.
InventorJean-Daniel Doutremepuich
Life of this patent
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Abstract
Topical compositions containing from 0.01% to 0.09% by weight of adapalene or salts thereof are useful for the treatment or prevention of keratinization disorders, particularly acne, and additionally contain at least one gelling agent selected from among carbomers, polysaccharides, cellulose and its derivatives, copolymers of acrylate and of alkyl acrylate, copolymers of acrylamide and of sodium acrylamido-2-methylpropanesulfonate, and xanthan gum.
Claims19
A topically applicable pharmaceutical composition useful for the treatment or prevention of keratin disorders, comprising from 0.01% to 0.09% by weight of adapalene or salts thereof, and which additionally comprises at least one gelling agent selected from the group consisting of carbomers, polysaccharides, magnesium aluminum silicates, acrylic polymers coupled to hydrophobic chains, modified starches, polyacrylamides, copolymers of acrylate and of alkyl acrylate, copolymers of acrylamide and of sodium acrylamido-2-methylpropanesulfonate, acrylate/C10-C30 alkyl acrylate crosspolymers or cellulose and derivatives thereof formulated into a topically applicable, pharmaceutically acceptable carrier therefor.
Dependencies are inferred from the claim text.