Novel Receptor Antagonists and Their Methods of Use

A compound of formula (I), or a pharmaceutically acceptable salt thereof:

• wherein:
• R1 represents unsubstituted methyl, ethyl, C3-5 cycloalkyl, pyridinylmethyl-, phenyl or benzyl;
• R2 and R3 independently represent hydrogen, halogen, C1-6 alkyl, arylmethyl-, C2-6 alkenyl, C2-6 alkynyl or C3-6 cycloalkylmethyl-;
• and any of said C1-6 alkyl, arylmethyl-, C2-6 alkenyl, C2-6 alkynyl or C3-6 cycloalkylmethyl- is optionally substituted with 1, 2 or 3 halogen atoms;
• R4, R5 and R6 independently represent hydrogen, fluorine or methyl;
• and
• R7, R8, R9, R10 and R11 independently represent hydrogen, halogen, cyano, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl or phenyl, and any of said C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl or phenyl is optionally substituted with 1, 2 or 3 halogen atoms;
• or R10 and R11 together with the carbon atoms to which they are attached form a benzene ring which is optionally substituted with 1, 2 or 3 halogen atoms;
• with the proviso that when R7 and R11 are both selected from hydrogen or fluorine, at least one of R8, R9 and R10 is a halogen atom, or R8, R9 and R10 are selected from the group consisting of hydrogen and CF3 and one, but not more than one, of R8, R9 and R10 is CF3.