Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use

A compound represented by formula I:

• or a pharmaceutically acceptable salt or solvate thereof wherein:
• ring A represents a phenyl or naphthyl group;
• each R1 and R2 represents H or is selected from the group consisting of halo, CN, OH, NO2, CO2Ra, NRaRb, S(O)pRa, C1-10alkyl, C2-10alkenyl or C1-10alkoxy, the alkyl and alkenyl portions of, C1-10alkyl, C2-10alkenyl and C1-10alkoxy being optionally substituted with 1-5 halo atoms up to perhalo;
• and further optionally substituted with 1 group selected from OH, oxo and C1-6alkoxy;
• p represents 0, 1 or 2;
• each Ra and Rb independently represents H or C1-4alkyl optionally substituted with 1-5 halo atoms up to perhalo;
• and further optionally substituted with 1 group selected from OH, oxo and C1-6alkoxy;
• R3 represents C1-6alkyl or C2-6alkenyl, each optionally substituted with 1-5 halo atoms up to perhalo, and further optionally substituted with 1 group selected from OH, oxo and C1-6alkoxy, and
• R4 represents H or C1-4alkyl optionally substituted with 1-3 halo atoms up to perhalo and 1 phenyl ring.