Composition and method for improved bioavailability and enhanced brain delivery of 5 5-diphenyl barbituric acid
AssigneeTaro Pharmaceutical Industries Ltd.
InventorsDaniella Gutman, Barrie Levitt, Daniel Moros, Avraham Yacobi, Howard Rutman
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Abstract
The present invention relates to a composition and a method of delivering a barbituric acid derivative to the central nervous system of a mammal in need of treatment for neurological conditions. In particular, the present invention relates to a method of administering an oral dosage form of a sodium salt of 5,5-diphenyl barbituric acid to enhance the bioavailability of 5,5-diphenyl barbituric acid and brain delivery of same.
Claims23
1-48. (canceled)
An oral dosage form comprising an isolated salt of 5,5-diphenyl barbituric acid and a pharmaceutically acceptable excipient.
A pharmaceutical product comprising an isolated salt form of 5,5-diphenyl barbituric acid.
61-62. (canceled)
(canceled)
Dependencies are inferred from the claim text.