Use of N-Phenyl-2-Pyrimidineamine Derivatives Against Mast Cell-Based Diseases Like Allergic Disorders
OwnerMichael Heinrich, Kenichi Koike +3inventors
InventorsMichael Heinrich, Kenichi Koike, Atsushi Komiyama, Motowo Nakajima, Kouichi Takeuchi
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Abstract
Use of the N-phenyl-2-pyrimidine-amine derivatives of formula I, in which the symbols and substituents have the meaning as given herein in free form or in pharmaceutically acceptable salt form in the manufacture of a pharmaceutical composition for the treatment of allergic rhinitis, allergic dermatitis, drug allergy or food allergy, angioedema, urticaria, sudden infant death syndrome, bronchopulmonary aspergillosis, multiple sclerosis or mastocytosis;
Claims4
A method of treating a warm blooded animal suffering from systemic mastocytosis comprising administering a therapeutically effective amount of N-5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.