US 2010/0144700 A1 · HETEROCYCLIC-CARBONYL-DIAZABICYCLOALKANES AS MODULATORS OF THE NEURONAL NICOTINIC ACETYLCHOLINE ALPHA 4 BETA 2, SUBTYPE RECEPTOR FOR THE TREATMENT OF CNS RELATED DISORDERS

Abstract

A compound of Formula 1: A-C(O)-Cy, wherein A is a diazabicyclic core, containing 7, 8, or 9 ring atoms, and selected from the following: 2,6-diazabicyclo[3.2.0]heptane; 3,6-diazabicyclo[3.ZO]heptane; 2,7-diazabicyclo[4.2.0]octane; 3,7-diazabicyclo[4.2.0]octane; 3,8-diazabicyclo[4.2.0]octane; 2,7-diazabicyclo[3.3.0]octane; 2,7-diazbicyclo[4.3.0]nonane; 2,8-diazbicyclo[4.3.0]nonane; 3,7-diazabicyclo[4.3.0]nonane; 3,8-diazabicyclo[4.3.0]nonane; 3,9-diazabicyclo[4.3.0]nonane; 2,6-diazabicyclo[3.2.1]octane; 3,6-diazabicyclo[3.2.1]octane; wherein the diazabicycle is attached as a radical to the depicted carbonyl via either one of the two ring nitrogen atoms, such that the carbonyl forms an amide bond with the ring nitrogen; Cy is a heteroaryl group; The compounds exhibit selectivity for, and bind with high affinity to, neuronal nicotinic receptors of the α402 subtype in the central nervous system (CNS). The compounds and compositions can be used to treat and/or prevent a wide variety of conditions or disorders, particularly CNS disorders. The compounds are believed to: (i) alter the number of nicotinic cholinergic receptors of the brain of the patient, (ii) exhibit neuroprotective effects, and (iii) when employed in effective amounts, not result in appreciable adverse side effects, namely side effects such as significant Increases in blood pressure and heart rate, significant negative effects upon the gastrointestinal tract, and significant effects upon skeletal muscle.

Claims18

Dependent claims

A compound of Formula 1:

A-C(O)-Cy Formula 1
or a pharmaceutically acceptable salt thereof,
wherein A is a diazabicyclic core, containing 7, 8, or 9 ring atoms, and selected from the following:
wherein the diazabicycle is attached as a radical to the depicted carbonyl via either one of the two ring nitrogen atoms, such that the carbonyl forms an amide bond with the ring nitrogen;
Cy is a heteroaryl group selected from the group consisting of 2-furanyl, 3-furanyl, 2-thienyl, 3-thienyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 1,3,4-oxadiazol-2-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 1,3,4-thiadiazol-2-yl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl, 3-pyridinyl, and 4-pyridinyl, each of which may be optionally substituted with up to three non-hydrogen substituents selected from the group consisting of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, heteroaryl, alkylaryl, arylalkyl, halogen, —OR′, —NR′R″, haloalkyl, —CN, —NO2, —C≡CR′, —SR′, —N3, —C(═O)NR′R″, —NR′C(═O)R″, —C(═O)R′, —C(═O)OR′, —OC(═O)R′, —OC(═O)NR′R″, —NR′C(═O)OR″, —SO2R′, —SO2NR′R″, and —NR′SO2R″;
wherein each of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, heteroaryl, alkylaryl, or arylalkyl may be substituted with one or more substituents selected from the group consisting of halogen, —OR′, —NR′R″, haloalkyl, —CN, —NO2, —C≡CR′, —SR′, —N3, —C(═O)NR′R″, —NR′C(═O)R″, —C(═O)R′, —C(═O)OR′, —OC(═O)R′, —C(═O)NR′R″, —NR′C(═O)O R″, —SO2R′, —SO2NR′R″, and —NR′SO2R″ where R′ and R″ are individually selected from the group consisting of hydrogen, alkyl, cycloalkyl, heterocyclyl, aryl, heteroaryl, and arylalkyl, or R′ and R″ can combine with the atoms to which they are attached to form a 3- to 8-membered cyclic functionality.

3 more elements

A method for treating central nervous system disorders, comprising administering a compound of Formula 1:

A-C(O)-Cy Formula 1
or a pharmaceutically acceptable salt thereof,
wherein A is a diazabicyclic core, containing 7, 8, or 9 ring atoms, and selected from the following:
wherein the diazabicycle is attached as a radical to the depicted carbonyl via either one of the two ring nitrogen atoms, such that the carbonyl forms an amide bond with the ring nitrogen;
Cy is a heteroaryl group selected from the group consisting of 2-furanyl, 3-furanyl, 2-thienyl, 3-thienyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 1,3,4-oxadiazol-2-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 1,3,4-thiadiazol-2-yl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl, 3-pyridinyl, and 4-pyridinyl, each of which may be optionally substituted with up to three non-hydrogen substituents selected from the group consisting of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, heteroaryl, alkylaryl, arylalkyl, halogen, —OR′, —NR′R″, haloalkyl, —CN, —NO2, —C≡CR′, —SR′, —N3, —C(═O)NR′R″, —NR′C(═O)R″, —C(═O)R′, —C(═O)OR′, —OC(═O)R′, —OC(═O)NR′R″, —NR′C(═O)R″, —SO2R′, —SO2NR′R″, and —NR′SO2R″;
wherein each of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, heteroaryl, alkylaryl, or arylalkyl may be substituted with one or more substituents selected from the group consisting of halogen, —OR′, —NR′R″, haloalkyl, —CN, —NO2, —C≡CR′, —SR′, —N3, —C(═O)NR′R″, —NR′C(═O)R″, —C(═O)R′, —C(═O)OR′, —OC(═O)R′, —C(═O)NR′R″, —NR′C(═O)OR″, —SO2R′R″, and —NR′SO2R″ where R′ and R″ are individually selected from the group consisting of hydrogen, alkyl, cycloalkyl, heterocyclyl, aryl, heteroaryl, and arylalkyl, or R′ and R″ can combine with the atoms to which they are attached to form a 3- to 8-membered cyclic functionality.

3 more elements

A pharmaceutical composition comprising a compound of Formula 1:

A-C(O)-Cy Formula 1
or a pharmaceutically acceptable salt thereof,
wherein A is a diazabicyclic core, containing 7, 8, or 9 ring atoms, and selected from the following:
wherein the diazabicycle is attached as a radical to the depicted carbonyl via either one of the two ring nitrogen atoms, such that the carbonyl forms an amide bond with the ring nitrogen;
Cy is a heteroaryl group selected from the group consisting of 2-furanyl, 3-furanyl, 2-thienyl, 3-thienyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl, 1,3,4-oxadiazol-2-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 1,3,4-thiadiazol-2-yl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl, 3-pyridinyl, and 4-pyridinyl, each of which may be optionally substituted with up to three non-hydrogen substituents selected from the group consisting of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, heteroaryl, alkylaryl, arylalkyl, halogen, —OR′, —NR′R″, haloalkyl, —CN, —NO2, —C≡CR′, —SR′, —N3, —C(═O)NR′R″, —NR′C(═O)R″, —C(═O)R′, —C(═O)OR′, —OC(═O)R′, —OC(═O)NR′R″, —NR′C(═O)OR″, —SO2R′, —SO2NR′R″, and —NR′SO2R″;
wherein each of alkyl, alkenyl, heterocyclyl, cycloalkyl, aryl, heteroaryl, alkylaryl, or arylalkyl may be substituted with one or more substituents selected from the group consisting of halogen, —OR′, —NR′R″, haloalkyl, —CN, —NO2, —C≡CR′, —SR′, —N3, —C(═O)NR′R″, —NR′C(═O)R″, —C(═O)R′, —C(═O)OR′, —OC(═O)R′, —C(═O)NR′R″, —NR′C(═O)O R″, —SO2R′, —SO2NR′R″, and —NR′SO2R″ where R′ and R″ are individually selected from the group consisting of hydrogen, alkyl, cycloalkyl, heterocyclyl, aryl, heteroaryl, and arylalkyl, or R′ and R″ can combine with the atoms to which they are attached to form a 3- to 8-membered cyclic functionality.

3 more elements

A compound selected from the group consisting of:

2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
3-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
3-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(furan-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(furan-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(furan-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(furan-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(2-methylfuran-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(2-methylfuran-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(oxazol-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(oxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(4-methyloxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(4-methyloxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-bromoisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(pyridin-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(pyridin-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(furan-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(furan-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(2-methylfuran-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(oxazol-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(oxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(4-methyloxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylisoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-bromoisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methoxyisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(pyridin-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
3-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane, and 6-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
or a pharmaceutically acceptable salt thereof.

591 more elements

A method for treating central nervous system disorders, comprising administering a salt of a compound selected from the group consisting of:

2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
3-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(Pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(Pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
3-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane 3-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[3.0]octane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(Pyridin-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(Pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(furan-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(furan-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(furan-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(furan-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(2-methylfuran-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(2-methylfuran-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(oxazol-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(oxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(4-methyloxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(4-methyloxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-bromoisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(pyridin-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(pyridin-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(Pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(furan-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(furan-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(2-methylfuran-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(oxazol-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(oxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(4-methyloxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylisoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-bromoisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methoxyisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(Pyridin-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
3-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane, and 6-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
or a pharmaceutically acceptable salt thereof.

590 more elements

A method for treating central nervous system disorders, comprising administering a compound selected from the group consisting of:

2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
6-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.0]heptane,
3-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
3-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
6-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.0]heptane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
7-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.2.0]octane,
3-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
7-(Pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.2.0]octane,
3-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
3-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
8-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.2.0]octane,
2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.3.0]octane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
7-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[3.3.0]octane,
2-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(furan-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylfuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-chlorofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-bromofuran-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(furan-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(2-methylfuran-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-2-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(4-methyloxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-3-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-bromoisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
7-(pyridin-4-ylcarbonyl)-2,7-diazabicyclo[4.3.0]nonane,
2-(furan-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(furan-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylfuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-chlorofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-bromofuran-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(furan-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(furan-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(2-methylfuran-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(2-methylfuran-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(oxazol-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-2-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(oxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(4-methyloxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(4-methyloxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-3-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(isoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-bromoisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
2-(pyridin-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
8-(pyridin-4-ylcarbonyl)-2,8-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(furan-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylfuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-chlorofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-bromofuran-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(furan-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(2-methylfuran-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-2-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(oxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(4-methyloxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-3-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(5-methylisoxazol-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(isoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methylisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-bromoisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(3-methoxyisoxazol-5-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
7-(pyridin-4-ylcarbonyl)-3,7-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(furan-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylfuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-chlorofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-bromofuran-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(furan-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(2-methylfuran-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-2-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(oxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(4-methyloxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-3-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(5-methylisoxazol-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(isoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methylisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-bromoisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(3-methoxyisoxazol-5-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
8-(pyridin-4-ylcarbonyl)-3,8-diazabicyclo[4.3.0]nonane,
3-(furan-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(furan-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylfuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-chlorofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-bromofuran-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(furan-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(furan-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(2-methylfuran-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(2-methylfuran-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(oxazol-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(oxazol-2-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(oxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(oxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(4-methyloxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(4-methyloxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylisoxazol-3-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(5-methylisoxazol-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(isoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(isoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methylisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-bromoisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(3-methoxyisoxazol-5-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
3-(pyridin-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
9-(pyridin-4-ylcarbonyl)-3,9-diazabicyclo[4.3.0]nonane,
2-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(furan-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylfuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-chlorofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-bromofuran-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(furan-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(2-methylfuran-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(oxazol-2-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(oxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(4-methyloxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-3-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-bromoisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
2-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
6-(pyridin-4-ylcarbonyl)-2,6-diazabicyclo[3.2.1]octane,
3-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(furan-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylfuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-chlorofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-bromofuran-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(furan-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(2-methylfuran-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(oxazol-2-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(oxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(4-methyloxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-3-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(5-methylisoxazol-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(isoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methylisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-bromoisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
6-(3-methoxyisoxazol-5-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
3-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane, and
6-(pyridin-4-ylcarbonyl)-3,6-diazabicyclo[3.2.1]octane,
or a pharmaceutically acceptable salt thereof.

592 more elements

Dependencies are inferred from the claim text.

Heterocyclic-carbonyl-diazabicycloalkanes as modulators of the neuronal nicotinic acetylcholine alpha 4 beta 2, subtype receptor for the treatment of cns related disorders

Life of this patent

Heterocyclic-carbonyl-diazabicycloalkanes as modulators of the neuronal nicotinic acetylcholine alpha 4 beta 2, subtype receptor for the treatment of cns related disorders

Life of this patent

Abstract

Claims18