1,2-diazetidin-3-one derivatives and drugs containing same

A 1,2-diazetidin-3-one derivative represented by the following general formula (1) or salt thereof, or their solvate:

• [wherein A ring represents a saturated C3-10 carbocyclic group,
• B ring represents a C3-8 cycloalkyl group, C3-8 cycloalkenyl group, C6-14 aryl group or a 5- to 14-membered heteroaryl group,
• R1, R2 and R3 represent the same or different and are a hydrogen atom, halogen atom, hydroxyl group, carboxyl group, carbamoyl group or C1-6 alkyl group,
• R4 and R5 represent the same or different and are a hydrogen atom or C1-6 alkyl group,
• R6, R7 and R8 represent the same or different and are a hydrogen atom, halogen atom, hydroxyl group, nitro group, cyano group, amino group (that may be substituted with a sulfonyl group or acyl group), C1-6 alkyl group, halo C1-6 alkyl group, C1-6alkoxy group (that may be substituted with a C1-6 alkoxy group), C6-10 aryl group, C2-6 alkanoyloxy group, C1-6 alkylthio group, C1-6 alkylsulfinyl group or C1-6 alkylsulfonyl group, or R6 and R7 may together form a C1-3 alkylenedioxy group,
• L represents a single bond, C1-6 alkylene chain, C2-6 alkenylene chain, —(C1-6 alkylene)-O—, —CO—X— or —SO2—Y—,
• X represents a single bond, —N(R9)—, —O—(C1-6 alkylene)-, —(C1-6 alkylene)-O—, —(C1-6 alkylene)-O—(C1-6 alkylene)- or —(C1-6 alkylene)-S—,
• R9 represents a hydrogen atom, C1-6 alkyl group or acyl group, and
• Y represents a single bond or C1-6 alkylene chain].