Topically applicable anti-inflammatory o/w emulsions comprising pro-penetrating glycols
AssigneeGalderma S.A.
InventorsSandrine Segura-Orsoni, Sophie Roumec
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Abstract
Stable, topically applicable, non-greasy and non-tacky oil-in-water (O/W) anti-inflammatory emulsions, useful, e.g., for the treatment of psoriasis, contain: a. a therapeutically effective amount of at least one steroidal anti-inflammatory agent, notably clobetasol propionate; b. a pro-penetrating system which includes at least one pro-penetrating glycol and at least one other pro-penetrating agent; and c. at least one polymeric emulsifier not sensitive to electrolytes, for example not an acrylate/C10-C30 alkyl acrylate copolymer, formulated into a topically applicable, pharmaceutically acceptable vehicle therefor.
Claims18
A stable, topically applicable, non-greasy and non-tacky oil-in-water (O/W) anti-inflammatory emulsion, comprising:
- a. a therapeutically effective amount of clobetasol propionate;
- b. a pro-penetrating system which comprises at least one pro-penetrating glycol and at least one other pro-penetrating agent;
- and
- c. at least one polymeric emulsifier not sensitive to electrolytes, formulated into a topically applicable, pharmaceutically acceptable vehicle therefor;
- said emulsion excluding acrylate/C10-C30 alkyl acrylate crosspolymers.
Dependencies are inferred from the claim text.