Composition comprising a glycolytic inhibitor and a ring system comprising a sulphamate group for the treatment of cancer
AssigneeSterix Limited
InventorsSarah Louise Claire Tagg, Paul Alexander Foster, Simon Paul Newman, John Michael Reed, Atul Purohit, Barry Victor Lloyd Potter
Life of this patent
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Abstract
The present invention provides a composition comprising (a) a glycolytic inhibitor (b) a compound comprising a ring system substituted with at least one of a suiphamate group and an alkoxy group; wherein (a) and (b) are different.
Claims60
A composition comprising:
- (a) a glycolytic inhibitor;
- and
- (b) a compound comprising a ring system substituted with at least one of a sulphamate group and an alkoxy group;
- wherein (a) and (b) are different.
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A method of rendering a tumor susceptible to action by a glycolytic inhibitor comprising administering to a subject in need thereof a therapeutically effective amount of a compound comprising a ring system substituted with at least one of a sulphamate group or an alkoxy group.
A method of intensifying at least one of hypoxia and glycolysis in a tumor comprising administering to a subject in need thereof a therapeutically effective amount of a compound comprising a ring system substituted with at least one of a sulphamate group and an alkoxy group.
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Dependencies are inferred from the claim text.