Hepatopoietin and use thereof
AssigneeInstitute of Radiation Medicine, Academy of Milita
InventorsZuze Wu, Bingxing Shi, Chunping Cui, Shaojun Du, Danli Wu
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Abstract
Provided are a hepatopoietin PCn (HPPCn) and its homologous proteins, which can promote hepatocyte proliferation in vitro, promote liver regeneration in vivo, inhibit the growth of tumor cells and promote the apoptosis of tumor cells. The hepatopoietin PCn (HPPCn) and its homologous proteins are useful for the treatment of acute and chronic liver injury, or the treatment of liver fibrosis.
Claims21
1-5. (canceled)
An isolated polypeptide comprising at least 95% sequence identity to SEQ ID NO:1.
An isolated polypeptide comprising the amino acid sequence SEQ ID NO:1.
Dependencies are inferred from the claim text.