Methods of Inhibiting Metastatic Cancer by Administration of Streptolysin O
AssigneeMilkhaus Laboratory, Inc.
InventorJohn McMichael
Life of this patent
Estimating the term…
Abstract
The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
Claims18
1-62. (canceled)
A method of inhibiting metastasis of cancer in a subject comprising administering streptolysin O (SLO) to the subject in an amount effective to inhibit metastasis of the tumor.
A method of inhibiting or suppressing metastasis of cancer in a subject comprising administering to said subject a combination therapy comprising
- (a) streptolysin O(SLO) and
- (b) a MMP inhibitor
- wherein the combination therapy is administered in an amount effective to inhibit or suppress metastasis of cancer in the subject.
A method of inhibiting or suppressing metastasis of a cancer cell, the method comprising contacting the cancer cell with streptolysin O (SLO) in an amount effective to inhibit or suppress metastasis of the cancer cell.
Dependencies are inferred from the claim text.