Methods of predicting cancer lethality using replikin counts

A method of predicting an expansion of a malignancy comprising:

• determining a mean Replikin Count and a standard deviation of said mean Replikin Count for a plurality of cells of a first malignancy for a first time period in a first anatomic region or for a first plurality of malignancies;
• determining a Replikin Count of at least one other cell of the first malignancy, at least one cell of a metastasis of the first malignancy, or at least one cell of a malignancy of unknown origin or unknown type in a subject suffering from the first malignancy at a second time period and/or in a second anatomic region, wherein said second time period is different from said first time period and/or said second anatomic region is different from said first anatomic region, or determining a Replikin Count of at least one cell of a second malignancy in a different subject;
• and
• predicting an expansion of said first malignancy, said metastasis of said first malignancy, said malignancy of unknown origin or unknown type, or said second malignancy in a different subject if the Replikin Count of said at least one cell is greater than the mean Replikin Count of the plurality of cells of said malignancy from said first time period and from said first anatomic region plus one standard deviation of the mean Replikin Count of the plurality of cells of said malignancy from said first time period and from said first anatomic region or if the Replikin Count of said at least one cell is greater than the mean Replikin Count of the first plurality of malignancies plus one standard deviation of the mean Replikin Count of the first plurality of malignancies.

A method of predicting the lethality of a first malignancy comprising:

• determining a Replikin Count of a first malignancy;
• performing a regression analysis with the Replikin Count of a plurality of second malignancies versus the lethality of said plurality of second malignancies;
• and
• predicting the lethality of the first malignancy based on the regression analysis of the plurality of second malignancies.