Loading patent…
AssigneesPostech Academy-Industry Foundation, Korea University Industry and Academy Collaboration Foundation
InventorsYu-Kyoung Oh, Hyun-Gu Kang, Ji-Seok Kim, Jiang Ge, Ki-Su Kim, Ki-Tae Park, Su-Eun Han, Ga-Yong Shim, II-Hwan Cho, Sei-Kwang Hahn
Estimating the term…
The present invention relates to a delivery system for nucleic acid using a cationic polymer conjugate, and more specifically relates to a delivery system for nucleic acid comprising a cationic polymer conjugate prepared by conjugating hyaluronic acid or its derivative and polyethyleneimine, and a composition of delivering a nucleic acid into mammalian cell comprising a complex of the nucleic acid and a cationic polymer conjugate with electrostatic binding.
A composition for delivering a nucleic acid with 5 to 200 base pair length into a mammalian cell which comprises a cationic polymer conjugate obtained by conjugating polyethyleneimine and hyaluronic acid or its derivative.
A method of preparing a cationic polymer conjugate comprising conjugating polyethyleneimine and hyaluronic acid or its derivative which is a hyaluronic acid bound with a compound having two or more carboxyl groups.
Dependencies are inferred from the claim text.