Compositions, methods and uses for inducing viral growth
AssigneeTakeda Vaccines, Inc.
InventorsDan T. Stinchcomb, Jill A. Livengood, O'Neil Wiggan, Richard Kinney, Jorge Osorio
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Abstract
Embodiments herein report methods, compositions and uses for inducing and/or accelerating viral growth. In certain embodiments, methods, compositions and uses generally related to copolymer compositions for inducing viral growth, reducing lag time and/or increasing viral plaque size. In other embodiments, methods, compositions and uses of copolymer compositions can be for inducing flaviviral growth, reducing lag in growth and/or increasing plaque size.
Claims24
A composition for growing viral cultures comprising:
- one or more high molecular weight surfactants or copolymers;
- and
- optionally, a media,
- wherein the high molecular weight surfactants or copolymer accelerate growth of viral cultures.
A method for increasing viral growth rate comprising, administering to a host cell culture infected with a virus, a composition comprising one or more high molecular weight surfactants or copolymers wherein the composition increases viral growth rate.
A method for increasing viral growth rate comprising, administering a composition comprising one or more high molecular weight surfactants or copolymers to a host cell culture, before, during, or after viral infection of the host cell culture.
A method for increasing plaque size of a viral culture comprising, administering to a host cell culture infected with a virus, a composition comprising one or more high molecular weight surfactants or copolymers wherein the composition increases viral plaque size compared to a control viral culture without administering one or more high molecular weight surfactants or copolymers.
A method for reducing growth lag time of a viral culture comprising, administering to a host cell culture infected with a virus, a composition comprising one or more high molecular weight surfactants or copolymers wherein the composition reduces lag time of the viral cultures compared to a control viral culture without administering one or more high molecular weight surfactants or copolymers.
A kit for culturing viruses comprising;
- at least one container;
- a composition comprising one or more high molecular weight surfactants;
- and
- optionally, one or more viral cultures.
Dependencies are inferred from the claim text.