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US 2010/0143903 A1Published application
Methods of Detecting and Monitoring Cancer Using 3D Analysis of Centromeres
Assignee3D Signatures Inc.
InventorsSabine Mai, Yuval Garini, Rahul Sarkar, Bartholomeus J. Vermolen
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Abstract
The present application relates to a method of detecting and monitoring cancer or precancer in a cell using three-dimensional analysis to assess centromere organization. In addition, the application relates to a method and system for characterizing the 3D organization of centromeres.
Claims14
A method of detecting or monitoring cancer or precancer in a test cell from a subject comprising the steps:
- (a) characterizing centromere organization in the test cell using three-dimensional (3D) analysis;
- and
- (b) comparing the centromere organization in the test cell with the centromere organization of a control cell,
- wherein the comparison between the centromere organization of the test cell and the centromere organization of the control cell is used to detect or monitor cancer.
1 more element
A method of monitoring cancer treatment in a test cell from a subject comprising the steps:
- (a) characterizing centromere organization in the test cell using three-dimensional (3D) analysis;
- and
- (b) comparing the centromere organization in the test cell with the centromere organization of a control cell,
- wherein the comparison between the centromere organization of the test cell and the centromere organization of the control cell is correlated with cancer treatment.
1 more element
Dependencies are inferred from the claim text.