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US 2010/0143533 A1Published application
Nutritional supplement system
AssigneeShaklee Corporation
InventorsKuei-tu Chang, Carsten R. Smidt, John Castillo, William J. Mergens
Life of this patent
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Abstract
A multi-part nutritional supplement system supplies nutrients to a user at advantageous locations in the digestive tract. One type of dosage unit is formulated to release vitamin B12 in the stomach and intestines of the upper GI tract, advantageously in an amount that is greater than or at multiple levels of the DV (Daily Value) of vitamin B12.
Claims83
A nutritional supplement system for human subjects consisting essentially of:
- a first nutritional supplement dosage unit, the first dosage unit being formulated to release one or more nutrients in the stomach of a human subject;
- a second nutritional supplement dosage unit, the second dosage unit being formulated to release one or more nutrients in the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of nutrients that do not require release in the stomach and exposure to stomach acid for efficient digestion and absorption and that cause tolerance problems or are subject to a loss in biological activity when released in the stomach;
- a third nutritional supplement dosage unit, the third dosage unit being formulated to continually release one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time;
- and
- a fourth nutritional supplement dosage unit, the fourth dosage unit being formulated to release one or more supplement ingredients in the lower intestinal tract of the subject, the supplement ingredients being selected from the group consisting of nutrients and other supplement ingredients that are adversely affected by exposure to stomach acid or stomach digestion.
2 more elements
A method for delivering nutrients and probiotics to a human subject, the method comprising orally administering a nutritional supplement system consisting essentially of:
- a first nutritional supplement dosage unit, the first dosage unit being formulated to release one or more nutrients in the stomach of a human subject;
- a second nutritional supplement dosage unit, the second dosage unit being formulated to release one or more nutrients in the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of nutrients that do not require release in the stomach and exposure to stomach acid for efficient digestion and absorption and that cause tolerance problems or are subject to a loss in biological activity when released in the stomach;
- a third nutritional supplement dosage unit, the third dosage unit being formulated to continually release one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time;
- and
- a fourth nutritional supplement dosage unit, the fourth dosage unit being formulated to release one or more supplement ingredients in the lower intestinal tract of the subject, the supplement ingredients being selected from the group consisting of nutrients and other supplement ingredients that are adversely affected by exposure to stomach acid or stomach digestion.
2 more elements
A nutritional supplement system for human subjects consisting essentially of:
- a first nutritional supplement dosage unit, the first dosage unit being formulated to release one or more nutrients in the stomach of a human subject;
- a second nutritional supplement dosage unit, the second dosage unit being formulated to release one or more nutrients in the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of nutrients that do not require release in the stomach and exposure to stomach acid for efficient digestion and absorption and that cause tolerance problems or are subject to a loss in biological activity when released in the stomach;
- and
- a third nutritional supplement dosage unit, the third dosage unit being formulated to continually release one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time.
1 more element
A method for delivering nutrients to a human subject, the method comprising orally administering a nutritional supplement system consisting essentially of:
- a first nutritional supplement dosage unit, the first dosage unit being formulated to release one or more nutrients in the stomach of a human subject;
- a second nutritional supplement dosage unit, the second dosage unit being formulated to release one or more nutrients in the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of nutrients that do not require release in the stomach and exposure to stomach acid for efficient digestion and absorption and that cause tolerance problems or are subject to a loss in biological activity when released in the stomach;
- and
- a third nutritional supplement dosage unit, the third dosage unit being formulated to continually release one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time.
1 more element
A nutritional supplement system for human subjects consisting essentially of:
- a immediate release nutritional supplement dosage unit, the dosage unit being formulated to release one or more nutrients in the stomach of a human subject;
- and
- a sustained release nutritional supplement dosage unit, the sustained release dosage unit being formulated to continually release one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time.
A method for delivering nutrients to a human subject, the method comprising orally administering a nutritional supplement system consisting essentially of:
- a immediate release nutritional supplement dosage unit, the immediate release dosage unit being formulated to release one or more nutrients in the stomach of a human subject;
- and
- a sustained release nutritional supplement dosage unit, the sustained release dosage unit being formulated to continually release one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time.
A method for delivering nutrients and probiotics to a human subject, the method comprising:
- providing one or more nutrients in the stomach of a human subject;
- providing one or more nutrients in the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of nutrients that do not require release in the stomach and exposure to stomach acid for efficient digestion and absorption and that cause tolerance problems or are subject to a loss in biological activity when released in the stomach;
- continually providing one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time;
- and
- providing one or more supplement ingredients in the lower intestinal tract of the subject, the supplement ingredients being selected from the group consisting of nutrients and other supplement ingredients that are adversely affected by exposure to stomach acid or stomach digestion.
2 more elements
A method for delivering nutrients to a human subject, the method comprising:
- providing one or more nutrients in the stomach of a human subject;
- providing one or more nutrients in the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of nutrients that do not require release in the stomach and exposure to stomach acid for efficient digestion and absorption and that cause tolerance problems or are subject to a loss in biological activity when released in the stomach;
- and
- continually providing one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time.
1 more element
A method for delivering nutrients to a human subject, the method comprising:
- providing one or more nutrients in the stomach of a human subject;
- and
- continually providing one or more nutrients starting in the stomach and continuing into the upper intestinal tract of the subject, the one or more nutrients being selected from the group consisting of water-soluble nutrients and other nutrients that are typically very rapidly absorbed and are best delivered by sustained release so as to maintain an elevated concentration in the body over time.
An oral nutritional supplement dosage unit for use by a human subject wherein:
- the dosage unit comprises vitamin B12;
- and
- the dosage unit is a sustained release dosage unit that provides for sustained release of the vitamin B12, starting in the stomach and continuing into the small intestine of a human subject over a period of time.
An oral nutritional supplement dosage unit for use by a human subject wherein:
- the dosage unit is a tablet or caplet comprising
- from 30 mg to 750 mg of vitamin C,
- from 25 mg to 400 mg of calcium,
- from 1 mg to 40 mg of vitamin B1,
- from 1 mg to 40 mg of vitamin B2,
- from 10 mg to 300 mg of vitamin B5,
- from 1 mg to 40 mg of vitamin B6,
- from 6 mcg to 500 mcg of vitamin B12,
- from 1 mg to 100 mg of bioflavonoid complex, and
- from 5 mg to 300 mg of quercetin;
- and
- the dosage unit is a sustained release dosage unit that provides for sustained release of the vitamin B12, starting in the stomach and continuing into the small intestine of a human subject over a period of time sufficient to provide elevated plasma levels of vitamin B12 for a period of at least 12 hours after ingestion.
9 more elements
A method for the delivery of vitamin B12 to a human subject, the method comprising orally administering to a human subject a sustained release nutritional supplement dosage unit wherein:
- the dosage unit comprises vitamin B12;
- and
- the dosage unit is formulated to release the vitamin B12, starting in the stomach and continuing into the upper intestinal tract.
A method for the delivery of vitamin B12 to a human subject, the method comprising orally administering to a human subject a sustained release nutritional supplement dosage unit wherein:
- the dosage unit is a tablet or caplet comprising
- from 30 mg to 750 mg of vitamin C,
- from 25 mg to 400 mg of calcium,
- from 1 mg to 40 mg of vitamin B1,
- from 1 mg to 40 mg of vitamin B2,
- from 10 mg to 300 mg of vitamin B5,
- from 1 mg to 40 mg of vitamin B6,
- from 6 mcg to 500 mcg of vitamin B12,
- from 1 mg to 100 mg of bioflavonoid complex, and
- from 5 mg to 300 mg of quercetin;
- and
- the dosage unit is formulated to release the vitamin B12, starting in the stomach and continuing into the upper intestinal tract sufficient to provide elevated plasma levels of vitamin B12 for a period of at least 12 hours after ingestion.
9 more elements
Dependencies are inferred from the claim text.