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AssigneesHypoxi Co., Ltd., Sun Mok Institute Education Foundation
InventorsJong Won Lee, Yae Sil Kim, Kyung Sik Song, Hyung Soo Han, Jung Hee Jang, Chae Ha Yang, Sun Ha Lim
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The present invention relates to a composition comprising a starch or total dietary fiber which improves the cell viability, specifically, the inventive starch and total dietary fiber isolated from the extract of Gramineae plant and the components therefrom improved the cell viability when the cells were incubated under hypoxic condition, or in the presence of beta-amyloid and 6-hydroxydopamine treatment, as well as prevented and treated myocardiac infarction, cerebral infarction and vascular dementia, or alleviated memory loss, all of which were proven using rats as the respective animal models. Therefore, they can be used as therapeutics or health care food for preventing and treating ischemic diseases or degenerative brain diseases.
A pharmaceutical composition comprising a starch or total dietary fiber as an active ingredient for the prevention and treatment of ischemic diseases and degenerative brain diseases.
A pharmaceutical composition comprising at least one component selected from the group consisting of arabinoxylan, beta-glucan, arabinose and xylose as active ingredients for the prevention and treatment of ischemic diseases and degenerative brain diseases.
A use of a starch or total dietary fiber for the preparation of therapeutic agent for the prevention and treatment of ischemic diseases and degenerative brain diseases in mammal and human in need thereof.
A use of at least one component selected from the group consisting of arabinoxylan, beta-glucan, arabinose and xylose for the preparation of therapeutic agent for the prevention and treatment of ischemic diseases and degenerative brain diseases in mammal and human in need thereof.
A method of preventing and treating ischemic diseases and degenerative brain diseases in a human or mammal comprising administration of an effective amount of a starch or total dietary fiber to said human or mammal, together with a pharmaceutically acceptable carriers or adjuvants thereof.
A method of treating and preventing ischemic diseases and degenerative brain diseases in a human or mammal comprising administration of an effective amount of at least one component selected from the group consisting of arabinoxylan, beta-glucan, arabinose and xylose to said human or mammal, together with a pharmaceutically acceptable carriers or adjuvants thereof.
A health care food comprising a starch or total dietary fiber as an active ingredient for the prevention and improvement of ischemic diseases or degenerative brain diseases.
A health care food comprising at least one component selected from the group consisting of arabinoxylan, beta-glucan, arabinose and xylose as an active ingredient for the prevention and improvement of ischemic diseases or degenerative brain diseases.
Dependencies are inferred from the claim text.