Infusion solution for peripheral intravenous administration
AssigneeAjinomoto Co., Inc.
InventorsMutsuo SHIGETA, Kazuhiro ABIKO
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AssigneeAjinomoto Co., Inc.
InventorsMutsuo SHIGETA, Kazuhiro ABIKO
Estimating the term…
There is provided an infusion solution for peripheral intravenous administration comprising a multichamber vessel constructed in a connectable manner, which separately houses a sugar solution containing sugars, electrolytes and vitamin B1, and an amino acid solution containing amino acids, electrolytes and a sulfite, whereby the vitamin B1 and amino acids are stably maintained. In the infusion solution for peripheral intravenous administration, the sugar solution contains calcium gluconate, contains no greater than 1.4 g/L sodium lactate, has a pH of 4.0-4.7 and has a titratable acidity of 2-4, the amino acid solution contains 4.0-8.0 g/L sodium lactate, contains no calcium gluconate, has a pH of 6.8-7.2, contains free L-cysteine as cysteine and contains 0.05-0.2 g/L sodium hydrogen sulfite, and after the sugar solution and amino acid solution have been mixed, the infusion solution has a pH of 6.5-7.1 and a titratable acidity of 5-10.
An infusion solution for peripheral intravenous administration comprising a sugar solution containing sugars, a portion of electrolytes and vitamin B1, and an amino acid solution containing amino acids, a portion of electrolytes and a sulfite, separately housed in a multichamber vessel constructed in a connectable manner, wherein (1) the sugar solution contains calcium gluconate, contains no greater than 1.4 g/L sodium lactate, has a pH of 4.0-4.7 and has a titratable acidity of 2-4, (2) the amino acid solution contains 4-15 g/L sodium lactate, contains no calcium gluconate, has a pH of 6.8-7.2, contains free L-cysteine as cysteine and contains 0.05-0.2 g/L sodium hydrogen sulfite, and (3) after the sugar solution and amino acid solution have been mixed, the infusion solution for peripheral intravenous administration has an infusion pH of 6.5-7.1 and a titratable acidity of 5-10.
An infusion solution for peripheral intravenous administration comprising a sugar solution containing sugars, a portion of electrolytes and vitamin B1, and an amino acid solution containing amino acids, a portion of electrolytes and a sulfite, separately housed in a multichamber vessel with a connectable construction, wherein (1) the sugar solution contains calcium gluconate, contains no sodium lactate, has a pH of 4.0-4.5 and has a titratable acidity of 2-4, (2) the amino acid solution contains sodium lactate, contains no calcium gluconate, has a pH of 6.8-7.2, contains free L-cysteine as cysteine and contains 0.05-0.2 g/L sodium hydrogen sulfite, and (3) after the sugar solution and amino acid have been mixed, the infusion solution for peripheral intravenous administration has a pH of 6.5-7.1 and a titratable acidity of 5-10.
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