Combination treatment with strontium for the prophylaxis and/or treatment of cartilage and/or bone conditions
AssigneeOsteologix A/S
InventorsChristian Hansen, Henrik Nilsson, Stephan Christgau
Life of this patent
Estimating the term…
Abstract
A combination treatment, wherein a strontium-containing compound together with one or more active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality are administered for use in the treatment and/or prophylaxis of cartilage and/or bone conditions.
Claims57
A method for the treatment and/or prophylaxis of a cartilage and/or bone disease and/or conditions resulting in a dysregulation of cartilage and/or bone metabolism in a mammal, the method comprising administering to a subject in need thereof a) a strontium-containing compound and b) one or more further active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone.
A method for the prophylaxis and/or treatment of a disease or condition involving alteration in the turnover of cartilage and/or bone turnover, the method comprising administering to a subject in need thereof a strontium-containing compound together with one or more further active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality.
A method for the prophylaxis and/or treatment of a disease or condition involving alteration in the turnover of cartilage and/or bone turnover, as quantified with biochemical markers of either cartilage turnover or bone turnover, the method comprising administering to a subject in need thereof a strontium-containing compound together with one or more further active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality to a subject in need thereof.
A method for reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality in a subject in need thereof, the method comprising
- detecting the presence of elevated bone turnover by use of specific biochemical markers of bone turnover and/or decreased bone mineral density identified by X-ray measurement of a skeletal site in the subject;
- and
- administering to the subject a strontium-containing compound together with one or more further active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality.
50-51. (canceled)
A pharmaceutical composition comprising a) a strontium-containing compound and b) one or more further active substances capable of reducing the incidence of bone fracture and/or increasing bone density and/or improving healing of fractured bone and/or improving bone quality, together with one or more physiologically acceptable excipients.
Dependencies are inferred from the claim text.