Composition for Improving Skin Condition and Appearance
AssigneeArch Personal Care Products, L.P.
InventorJames V. Gruber
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Abstract
Disclosed is a cosmetic composition comprising prenylated isoflavonoid and a carrier, wherein the prenylated isoflavonoid is from about 0.0000001% to about 10%, preferably from 0.00001% to 1%, most preferably from 0.01% to 1%, by weight, based on the total weight of the composition. The active agent prenylated isoflavonoid induces a statistically significant upregulation of collagen 1A1 and elastin genes in normal human dermal fibroblasts. The composition is effective to stimulate the production of collagen and elastin and improve the appearance and condition of the skin.
Claims16
A composition comprising:
- (a) a safe and effective amount of prenylated isoflavonoid sufficient for increasing collagen 1A1 and elastin gene expression in normal human dermal fibroblasts;
- and
- (b) a cosmetically or dermatologically-acceptable carrier for said prenylated isoflavonoid;
- wherein said prenylated isoflavonoid is present in an amount of from about 0.0000001% to about 10%, and said carrier is present in an amount of from about 50% to about 99% based on the total weight of the composition.
A composition comprising a Maclura pomifera (Osage orange) fruit extract encapsulated in a delivery vehicle selected from a group consisting of liposome, maltodextrin, polymeric matrix, niasome and nanoparticle, wherein said fruit extract is effective to increase collagen 1A1 and elastin gene expression in normal human dermal fibroblasts and wherein said fruit extract is present in an amount of from about 0.0000001% to about 10% based on the total weight of the composition.
A method for regulating skin condition comprising topically applying to skin a composition containing:
- (a) a safe and effective amount of prenylated isoflavonoid sufficient for increasing collagen 1A1 and elastin gene expression in normal human dermal fibroblasts;
- and
- (b) a cosmetically or determatologically acceptable carrier for said prenylated isoflavonoid;
- wherein said prenylated isoflavonoid is present in an amount of from about 0.0000001% to about 10%, said carrier is present in an amount of from about 50% to about 99% based on the total weight of the composition.
Dependencies are inferred from the claim text.