Analgesic composition of topically applied nonsteroidal antiinflammatory drugs and opioids
OwnerYuri Kolesnikovinventor
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Abstract
The present invention relates to pharmaceutical formulations comprising at least two compounds, one effecting opioid analgesia and one effecting cyclooxygenase 1 and 2 activity, in amounts sufficient to potentiate an antinociceptive response when both compounds are topically administered in a physiologically acceptable topical excipient. The pharmaceutical formulations of the present invention are used to prevent or relieve acute pain and chronic peripheral neuropathy and/or neuropathic inflammation in a patient in need of such treatment.
Claims18
A pharmaceutical formulation comprising at least two compounds, one effecting opioid analgesia and one effecting cyclooxygenase 1 and 2 activity, in amounts sufficient to potentiate an antinociceptive response when both compounds are topically administered in a physiologically acceptable topical excipient.
Use of at least two compounds, one effecting opioid analgesia and one effecting cyclooxygenase 1 and 2 activity, for the production of a topical pharmaceutical combination to prevent or relieve acute incisional pain and chronic peripheral neuropathy in a patient in need of such treatment.
Use of at least two compounds, one effecting opioid analgesia and one effecting cyclooxygenase 1 and 2 activity, for the production of a topical pharmaceutical combination to prevent or relieve neuropathic inflammation in a patient in need of such treatment.
Dependencies are inferred from the claim text.