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US 2010/0143437 A1Published application
Implantable analgesic
OwnerEdward J. Morris, W. Herbert Senftinventors
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Abstract
A method and device for implantable analgesics having a plurality of analgesia containing portions that are capable of being sequentially released.
Claims20
An implantable drug delivery vessel including;
- a first portion having a first concentration of a first drug therein,
- a second portion having a second concentration of a second drug therein,
- a first biodegradable medium containing the first drug;
- and
- a second biodegradable medium containing the second drug;
- the first and second biodegradable media being placed and composed such that when exposed to an internal portion of a body of the patient, the first and second media successively release the first drug in the first concentration and the second drug in the second concentration.
3 more elements
A method for providing sustained local anesthesia to a site in a subject, the method comprising:
- administering to the site a composition comprising:
- a delivery vessel comprising:
- a first anesthetic containing section, and
- a second anesthetic containing section completely surrounded by the first anesthetic containing section, wherein the first anesthetic containing section, when administered at the site degrades to release anesthetic and to expose the second anesthetic containing section.
1 more element
A biodegradable multi-layered vessel comprising:
- anesthetic, and
- a biocompatible, biodegradable polymer, degradation of a first layer of the biodegradable polymer releasing a first portion of the anesthetic and enables degradation of a second layer of the biodegradable polymer to release a second portion of the anesthetic, the second portion of the anesthetic being distinct from the first portion of the anesthetic and having a defined boundary therebetween.
A method of manufacturing an implantable drug delivery vessel, the method including the steps of;
- providing a first biodegradable medium containing a first volume of a first drug of a first concentration,
- providing a second biodegradable medium containing a second volume of a second drug of a second concentration, and
- surrounding the second biodegradeable medium with the first biodegradable medium such that when exposed to an internal portion of a body of the patient, the first and second media successively release the first drug in the first concentration and the second drug in the second concentration.
Dependencies are inferred from the claim text.