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US 2010/0143353 A1Published application
POLYPEPTIDES COMPRISING Fc FRAGMENTS OF IMMUNOGLOBULIN G (lgG) AND METHODS OF USING THE SAME
OwnerDavid M. Mosser, Shanjin Caoinventors
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Abstract
Polypeptides comprising at least a first and second Fc fragment of IgG that can be used to induce a stimulated cell to produce the anti-inflammatory cytokine Interleukin-10 and methods of using the same are disclosed herein.
Claims26
A polypeptide comprising:
- at least a first and second Fc fragment of IgG;
- at least one of said first Fc fragment of IgG comprising at least one CH2 domain and at least one hinge region;
- the first and second Fc fragments of IgG being bound through the at least one hinge region.
Dependencies are inferred from the claim text.