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AssigneeJapan AS Represented By President of National Cardiovascular Center
InventorsNoboru Murakami, Keiko Nakahara, Miho Hashimoto, Yujiro Hayashi, Kenji Kangawa
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The invention provides a spinal neuron damage treating agent for use in the treatment of spinal neuron damage, or an agent for promoting the proliferation of spinal neuronal precursor cells in the culture of spinal neuronal precursor cells, or an agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal precursor cells, and the like. The invention provides an agent that contains a substance (e.g., ghrelin) that acts on the growth hormone secretagogue-receptor as an active ingredient, the agent being a spinal neuron damage treating agent for use in the treatment of spinal neuron damage, or an agent for promoting the proliferation of cultured spinal neuronal precursor cells in the culture of spinal neuronal precursor cells, or an agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal precursor cells, and the like.
A spinal neuron damage treating agent containing a substance that acts on a growth hormone secretagogue-receptor or a pharmaceutically acceptable salt thereof as an active ingredient.
An agent for promoting the proliferation of spinal neuronal precursor cells in the culture of spinal neuronal precursor cells that contains a substance that acts on a growth hormone secretagogue-receptor or a salt thereof as an active ingredient.
An agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal precursor cells that contains a substance that acts on a growth hormone secretagogue-receptor or a pharmaceutically acceptable salt thereof as an active ingredient.
A method for promoting the proliferation of cultured spinal neuronal precursor cells, characterized by using a substance that acts on a growth hormone secretagogue-receptor or a salt thereof.
Dependencies are inferred from the claim text.