System for enriching a bodily fluid with a gas having occlusion detection capabilities

A gas-enrichment system having an extracorporeal circuit for enriching a bodily fluid of a patient with a gas-enriched fluid, comprising:

• an enclosure configured for receiving a gas-enrichment device, wherein said gas-enrichment device comprises a gas-enrichment chamber for enriching a physiologic fluid with the gas and a mixing chamber for mixing the gas-enriched physiologic fluid with the bodily fluid of the patient;
• a pumping assembly comprising a pump for controlling fluid flow through the extracorporeal circuit;
• and
• a controller for automatic control of gas-enrichment and extracorporeal circuit operations,
• wherein said system and said gas-enrichment device, when loaded into the system, provide a fluid path for the bodily fluid to circulate from the patient to the mixing chamber and back to the patient;
• wherein said controller is capable of controlling the pumping assembly and the gas-enrichment device to perform an automated sequence of actions to prime the gas-enrichment chamber with the physiologic fluid upon loading the gas-enrichment device, and to prime the fluid path with the bodily fluid upon receiving a priming command from the user;
• and
• wherein said controller is capable of detecting occlusions in the extracorporeal circuit and responding to different occlusion conditions to prevent forced shutdown/re-priming of the circuit.