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US 2010/0137932 A1Published application
Method and apparatus for optimizing electrical stimulation parameters using heart rate variability
AssigneeCardiac Pacemakers, Inc.
InventorsJoseph M. Pastore, Rodney W. Salo, Gerrard M. Carlson, Andrew P. Kramer, Jiang Ding, Yinghong Yu
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Abstract
A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to evaluate a plurality of parameter values for selecting an approximately optimal parameter value.
Claims20
A method comprising:
- starting a stimulation parameter optimization period on a periodic basis;
- sensing a cardiac signal;
- producing a plurality of parameter values for at least one stimulation parameter;
- delivering electrical stimulation pulses using the plurality of parameter values for the at least one stimulation parameter during the stimulation parameter optimization period;
- measuring a variance in cardiac cycle lengths over a predetermined period of time to produce at least one heart rate variability (HRV) parameter based on the cardiac signal sensed during the stimulation parameter optimization period;
- selecting an approximately optimal value for the at least one stimulation parameter from the plurality of parameter values, the approximately optimal value corresponding to a maximum value of the HRV parameter measured during the stimulation parameter optimization period.
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Dependencies are inferred from the claim text.