Fibrous Surgically Implantable Mesh
AssigneeNicast Ltd.
InventorsJean-Pierre Elisha Martinez, Alexander Dobson, Alon Shalev
Life of this patent
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Abstract
A fibrous mesh surgically implantable into a mammal internal cavity is disclosed. The aforesaid mesh has a laminar extra-cellular-like matrix structure. The mesh comprises a first layer characterized by porosity effective for mammal tissue infiltration into the first layer and a substantially non-porous second layer. The first layer is adapted to surgically adhere to a cavity wall in need of repair such that wall tissues infiltrate thereinto while the second layer is characterized by non-adhesion and adapted for non-traumatic contact to mammal viscera and omentum. The first layer is biodegradable and the second layer is tissue-integrated with the cavity wall.
Claims20
A fibrous mesh surgically implantable into a mammal internal cavity;
- said mesh has a laminar extra-cellular-matrix-like structure;
- said mesh comprises a first layer characterized by a porosity effective for mammal tissue infiltration into said first layer and a substantially non-porous bio-stable second layer;
- said first layer is adapted to surgically adhere to a cavity wall in need of repair such that wall tissues infiltrate thereinto while said second layer is characterized by non-adhesion and adapted for non-traumatic contact to mammal viscera and omentum;
- wherein said first layer is biodegradable and said second layer is biostable and tissue-supporting with said cavity wall.
A method of repairing a tissue aperture within a wall of a mammal internal cavity;
- said method comprises the steps of
- (a) providing an implantable mesh of a laminar extra-cellular-matrix-like structure comprising a first layer characterized by a predetermined porosity and a substantially non-porous second layer;
- said first layer is adapted to surgically adhere to a cavity wall in need of repair such that wall tissues infiltrate thereinto while said second layer characterized by non-adhesion and adapted for non-traumatic contact to mammal viscera and omentum;
- (b) inserting said mesh into a mammal cavity;
- and
- (c) tightly attaching said mesh to a mammal cavity wall;
- (d) infiltrating said wall tissues into said first layer;
- and
- (e) non-traumatically contacting said mammalian viscera by means of said second layer;
- wherein said method further comprises the steps of biodegrading said first layer and permanently residing said second layer on said wall with tissue support therebetween.
Dependencies are inferred from the claim text.