Degradation of phosphate esters by molybdocene and tungstocene derivatives
AssigneeLewis & Clark College
InventorLOUIS KUO
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Abstract
Degradation of phosphate esters, particularly neurotoxins and pesticides, is performed using metallocene derivatives, more particularly molybdocene and tungstocene derivatives. A metallocene derivative is hydrolyzed and then reacted with a phosphate ester. The preferred metallocene derivatives are molybdocene and tungstocene derivatives. The phosphate esters can include, but are not limited to, VX, VE, VG, VM, GB, GD, GA, GF, parathion, paraoxon, triazophos, oxydemeton-methyl, chlorpyrifos, fenitrothion and pirimiphos-methyl, representing both chemical warfare agents as well as pesticides and insecticides.
Claims14
A method for degrading a phosphate ester comprising:
- hydrolyzing a metallocene derivative;
- and
- reacting the hydrolyzed metallocene derivative with a phosphate ester, wherein the metallocene derivative is selected from the group consisting of:
- wherein R1-R20 are not all hydrogen;
- and
- wherein M1 and M2 are selected from the group consisting of molybdenum and tungsten;
- wherein X1 and X2 are hydrolyzable anions;
- wherein Y1 and Y2 are selected from the group consisting of O, S, OH, SH, OR and SR wherein R is further selected from the group consisting of linear, branched, saturated and unsaturated C1-C20 alkyl, C3-C20 cycloalkyl, C6-C20 aryl, C7-C20 alkylaryl, C7-C20 arylalkyl radicals;
- and
- wherein the phosphate ester is selected from the group consisting of:
A method for degrading a phosphate ester comprising:
- hydrolyzing a metallocene derivative;
- and
- reacting the hydrolyzed metallocene derivative with a phosphonothioate with the formula
- wherein the metallocene derivative is selected from the group consisting of
- wherein M is selected from the group consisting of molybdenum and tungsten;
- wherein X1 and X2 are hydrolyzable anions;
- wherein Y1 and Y2 are selected from the group consisting of O, S, OH, SH, OR and SR, wherein R is further selected from the group consisting of linear, branched, saturated and unsaturated C1-C20 alkyl, C3-C20 cycloalkyl, C6-C20 aryl, C7-C20 alkylaryl, C7-C20 arylalkyl radicals.
Dependencies are inferred from the claim text.