Poly-n-heterocyclic carbene transition metal complexes and n-heterocyclic carbene transition metal complexes for carbon-sulfur and carbon-oxygen coupling reactions
OwnerYugen Zhanginventor
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Abstract
Methods for carbon-sulfur (C—S) or carbon-oxygen (C—O) coupling reactions are provided. The methods involve the use of a transition metal complex comprising a heterocyclic carbene ligand complexed with a transition metal. Transition metal complexes comprising a heterocyclic carbene ligand complexed with nickel are also provided. The nickel heterocylic carbene complexes may be used for C—S or C—O coupling reactions.
Claims19
A method for carbon-sulfur (C—S) or carbon-oxygen (C—O) coupling comprising:
- a) mixing, in any order, a thiol-containing compound, an aryl halide and a transition metal complex to obtain C—S coupling;
- or
- b) mixing, in any order, an alkoxide or aryloxide, an aryl halide and a transition metal complex to obtain C—O coupling,
- wherein the transition metal complex comprises a heterocyclic carbene ligand complexed with a transition metal other than palladium.
A method for carbon-sulfur (C—S) or carbon-oxygen (C—O) coupling comprising:
- a) mixing, in any order, a thiol-containing compound, an aryl halide and a transition metal complex to obtain C—S coupling;
- or
- b) mixing, in any order, an alkoxide or aryloxide, an aryl halide and a transition metal complex to obtain C—O coupling,
- wherein the transition metal complex comprises a heterocyclic carbene ligand complexed with nickel.
A transition metal complex comprising a poly-N-heterocyclic carbene (p-NHC) complexed with nickel.
A transition metal complex comprising a heterocyclic carbene ligand represented by the formula:
- complexed with nickel.
Dependencies are inferred from the claim text.