N[S(4-ARYL-TRIAZOL-3-YL)alpha-MERCAPTOACETYL] -P-AMINO BENZOIC ACIDS AS HIV REVERSE TRANSCRIPTASE INHIBITORS

A compound of formula

• wherein:
• R1 is selected from the group consisting of Cl, Br, I, CH3, CF3, CHF2, and CH2F;
• X is O or NH;
• R2 is H, a pharmaceutically acceptable cation or C1-3 alkyl, when X is O;
• or
• XR2 is NHCH2CH2COOR13 or NHCH(R12)COOR13 where R12 is C1-4 alkyl or aryl-C1-4 alkyl and R13 a pharmaceutically acceptable cation or C1-3 alkyl;
• R3 is H or CH3;
• R0 is selected from the group consisting of Cl, Br, CF3 and methyl;
• RP is selected from the group consisting of methyl, ethyl, propyl, isopropyl, cyclopropylmethyl, and C3-6 cycloalkyl;
• R4, R5 and R6 are independently selected from the group consisting of H, F, Cl, Br, CH3, CF3, CFH2, CF2H, ethyl, isopropyl, cyclopropyl, OCH3, OH, OCF3, NH2 and NHCH3;
• and
• Q and Q′ are independently selected from N and CH.