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US 2010/0137571 A1Published application
Dengue serotype 1 attenuated strain
AssigneesSanofi Pasteur Limited, Centers for Disease Control and Prevention
InventorsRICHARD KINNEY, CLAIRE Y.H. KINNEY, VÉRONIQUE BARBAN, JEAN Lang, BRUNO GUY
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Abstract
The invention relates to live attenuated VDV1 (VERO-Derived Dengue serotype 1 virus) strains which have been derived from the wild-type dengue-1 strain 16007 by passaging on PDK and sanitization on Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV1 strain.
Claims4
An isolated nucleic acid which comprises the DNA sequence SEQ ID NO:
- 1 or its equivalent RNA sequence.
An isolated nucleic acid encoding the polyprotein having the sequence SEQ ID NO:41.
Dependencies are inferred from the claim text.