Derivatives of 1-piperazine- and 1-homopiperazine-carboxylates, preparation method thereof and use of same as inhibitors of the faah enzyme

A compound of the formula (I):

• wherein
• m represents an integer equal to 2;
• R1 represents a group chosen from phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, triazinyl, oxazolyl, triazolyl, imidazolyl, oxadiazolyl, thiadiazolyl, triazolyl, naphthyl, quinolyl, tetrahydroquinolyl, isoquinolyl, tetrahydroisoquinolyl, phthalazinyl, quinazolinyl, quinoxalinyl, cinnolinyl, naphthyridinyl, benzofuryl, dihydrobenzofuryl, benzothienyl, dihydrobenzothienyl, indolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benzisothiazolyl, benzimidazolyl, indazolyl, pyrrolopyridyl, furopyridyl, dihydrofuropyridyl, thienopyridyl, dihydrothienopyridyl, imidazopyridyl, imidazopyrimidinyl, pyrazolopyridyl, oxazolopyridyl, isoxazolopyridyl, thiazolopyridyl or isothiazolopyridyl;
• wherein said group is optionally substituted with one or more groups R3, which may be identical or different, or with a group R4;
• R2 represents a group of formula CHR5CONHR6;
• R3 represents a halogen atom or a hydroxyl, cyano, nitro, C1-6-alkyl, C1-6-alkoxy, C1-6-thioalkyl, C1-6-fluoroalkyl, C1-6-fluoroalkoxy, —O—(C2-3-alkylene)-, —O—(C1-3-alkylene)-O—, C1-6-fluorothioalkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-3-alkylene, piperidyl, benzyloxy, piperazinyl, pyrrolidinyl, morpholinyl, phenyloxy, NR7R8, NHCOR7, NHSO2R7, COR7, CO2R7, CONR7R8, SO2R7 or SO2NR7R8 group;
• R4 represents a group chosen from phenyl, benzofuryl, naphthyl, pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, triazinyl, oxazolyl, triazolyl, imidazolyl, oxadiazolyl, thiadiazolyl, triazolyl, quinolyl, tetrahydroquinolyl, isoquinolyl, tetrahydroisoquinolyl, phthalazinyl, quinazolinyl, quinoxalinyl, naphthyridinyl, cinnolinyl, benzothienyl, indolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benzisothiazolyl, benzimidazolyl, indazolyl, pyrrolopyridyl, furopyridyl, dihydrofuropyridyl, thienopyridyl, dihydrothienopyridyl, imidazopyridyl, imidazopyrimidinyl, pyrazopyridyl, oxazolopyridyl, isoxazolopyridyl, thiazolopyridyl or isothiazolo-pyridyl;
• wherein said group R4 is optionally substituted with one or more groups R3, which may be identical or different;
• R5 represents a hydrogen atom or a C1-3-alkyl group;
• R6 represents a hydrogen atom or a C1-6-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-3-alkylene group;
• and
• R7 and R8 represent, independently of each other, a hydrogen atom, a C1-3-alkyl group or a phenyl group;
• or
• a salt thereof.