Substituted pyrimidine derivatives

A compound having the general formula I:

• wherein:
• q is 0 or 1;
• R1 and R2 are independently selected from the group consisting of hydrogen and optionally substituted aryl-C1-6-alk(en/yn)yl, provided that R1 and R2 are not both hydrogen, or R1 and R2 together with the nitrogen to which they are attached form a 5 to 7 membered ring optionally containing a further heteroatom;
• R3 and R4 are independently selected from hydrogen, halogen, cyano, amino, C1-6-alk(en/yn)yl, C3-8-cycloalk(en)yl, halo-C1-6-alk(en/yn)yl, halo-C3-8-cycloalk(en)yl, C1-6-alk(en/yn)yloxy, C3-8-Cycloalk(en)yloxy, C3-8-cycloalk(en)yl-C1-6-alk(en/yn)yloxy, halo-C1-6-alk(en/yn)yloxy, halo-C3-8-cycloalk(en)yloxy and halo-C3-8-cycloalk(en)yl-C1-6-alk(en/yn)yloxy, provided that R3 and R4 are not both hydrogen;
• R5 is selected from the group consisting of C1-10-alk(en/yn)yl, C3-8-cycloalk(en)yl-C1-6-alk(en/yn)yl, optionally substituted aryl-C1-6-alk(en/yn)yl and optionally substituted aryl;
• or a pharmaceutically acceptable salt thereof.