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AssigneeSharp Kabuchiki Kaisha
InventorsYoshiroh Akagi, Kazuo Ban, Kyoko Seo, Naoya Ichimura, Atsushi Mizusawa
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A biosensor capable of highly sensitive detection of a recognition target substance while having structural stability is provided at low cost. The biosensor is for capturing and detecting a recognition target substance and includes a linker made of a hydrocarbon compound having two or more particular functional groups, a peptide serving as a molecular recognition substance directly bonded to one particular functional group of the linker, and a support directly bonded to the other particular functional group of the linker. Preferably, the particular functional groups each are a reaction product functional group of an epoxy group and an amino group. The peptide is an artificially synthesized peptide including three or more consecutive amino acid sequences, among amino acid sequences of a natural immunoglobulin, that exist in a part corresponding to a hypervariable area of the natural immunoglobulin.
A biosensor for capturing and detecting a recognition target substance, the biosensor comprising:
A method for producing a biosensor comprising the step of bringing a mixture solution of a peptide serving as a molecular recognition substance and a linker molecule made of a hydrocarbon compound with epoxy groups at both terminals thereof into contact with a support having on a surface thereof a functional group that bonds to an epoxy group, in order to directly bond the peptide to the linker molecule and directly bond the linker molecule to the support.
A biosensor comprising:
Dependencies are inferred from the claim text.