Membrane array and analytical device
AssigneeZBx Corporation
InventorShi Qinwei
Life of this patent
Estimating the term…
Abstract
A membrane array used to detect one or more analytes from a small sample of fluid with high sensitivity is provided. The membrane array can be employed in various analytical devices and is especially useful for identifying analytes from whole blood with minimal or negligible background interference.
Claims76
-50. (canceled)
An improved membrane array for rapid, highly efficient and highly sensitive detection of one or more analytes in a small sample volume, said membrane array comprising three or more porous membranes which are non-planar with respect to adjacent membranes.
The membrane array of claim 69, wherein one end of said analytical device is adapted to receive a removable cap, said cap facilitating the application of said sample using a sample transfer means to said membrane array.
An analytical device for the rapid detection of one or more components in a small volume of sample, the analytical device comprising:
- a membrane array having at least three overlapping porous membranes arranged in stair step configuration comprising;
- a first step adapted to receive a fluid sample and containing a detection reagent;
- a second step having a lower porosity than said first step;
- and
- a third step having a lower porosity than said second step and containing a capture reagent.
A method for determining the amount of analyte in a small volume fluid sample, said method comprising;
- to a membrane array comprising;
- a first step adapted to receive a fluid sample and containing a detection reagent;
- a second step having a lower porosity than said first step;
- and
- a third step having a lower porosity than said second step and containing a capture reagent;
- and
- applying a fluid sample to one end of said first step, wherein said fluid sample moves via capillary flow into and through said second step and then to said third step where detection of said analyte occurs.
Dependencies are inferred from the claim text.