Apheresis Tubing Set
OwnerGlen James Wicks Delaronde-Wiltoninventor
Life of this patent
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Abstract
An apheresis tubing set comprises a cryocyte bag for collecting cells separated during apheresis. The cryocyte bag may comprise a mixing compartment in fluid communication with a cell storage compartment, wherein the mixing compartment comprises a cryoprotectant port and a cell sample port and wherein the storage and mixing compartments are in fluid communication via a mix conduit. The cryocyte bag may comprise two or more independent cell storage compartments for collecting two or more aliquots of the cells
Claims51
An apheresis tubing set comprising a cryocyte bag for collecting cells separated during apheresis.
The tubing set of any one of the preceding claims wherein the cryoprotectant port is connected to a cryoprotectant inlet by a cryoprotectant conduit.
The tubing set of any one of the preceding claims wherein the cryoprotectant port is separated from the cryoprotectant inlet by a sterile barrier filter within the cryoprotectant conduit.
The tubing set of any one of the preceding claims wherein the cryocyte bag comprises two or more independent cell storage compartments for collecting two or more aliquots of the cells.
The tubing set of any one of the preceding claims wherein the mix conduit(s):
- (a) are sealable (for example, heat sealable);
- and/or
- (b) comprise patency tube(s).
The tubing set of any one of the preceding claims wherein the cryocyte bag is of thermoplastic material.
The tubing set of any one of the preceding claims wherein the cryocyte bag is of a fluorocarbon resin.
The tubing set of any one of the preceding claims wherein the mixing and storage compartment(s) are releasably joined.
The tubing set of any one of the preceding claims wherein the cryocyte bag is tailed with thermoplastic tubing.
The tubing set of any one of the preceding claims wherein at least some components (e.g. the vessel(s) and/or interconnecting tube(s)) of the tubing set other than the cryocyte bag are of PVC.
The tubing set of any one of the preceding claims which is a leukapheresis tubing set.
The tubing set of any one of the preceding claims which is closed or functionally closed.
The tubing set of any one of the preceding claims wherein the compartments (e.g. the holding compartments) are releasably joined by at least one breakable bridge.
The tubing set of any one of the preceding claims further comprising a blood processing vessel.
The tubing set of any one of the preceding claims further comprising a sample vessel for holding an isolated tissue (e.g. peripheral blood, cord blood or bone marrow) sample.
The tubing set of any one of the preceding claims further comprising means (e.g. comprising a needle) for collecting an isolated blood or bone marrow sample from an individual.
The tubing set of any one of the preceding claims which is adapted for use in an automated leukapheresis device.
A cryocyte or leukocyte collect bag for use with the tubing set as defined in any one of the preceding claims.
A cryocyte bag for collecting cells separated during apheresis comprising one or more cell storage compartment(s) having a sample transfer port, wherein the sample transfer port comprises a patency tube.
Dependencies are inferred from the claim text.