Sour taste receptor compositions and methods
AssigneeDuke University
InventorsHiroaki Matsunami, Momoka Matsunami, Yoshiro Ishimaru
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Abstract
The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
Claims9
1-9. (canceled)
A cell line comprising recombinant cells which have been genetically engineered to express a functional sour taste receptor.
14-19. (canceled)
Dependencies are inferred from the claim text.