Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
AssigneeNexus Dx, Inc.
InventorGeorge Jackowski
Life of this patent
Estimating the term…
Abstract
A method for determining whether a subject has had a stroke and, if so, the type of stroke which includes analyzing the subject's body fluid for at least four selected markers of stroke, namely, myelin basic protein, S100 protein, neuronal specific enolase and a brain endothelial membrane protein such as thrombomodulin or a similar molecule. The data obtained from the analyses provide information as to the type of stroke, the onset of occurrence and the extent of brain damage and allow a physician to determine quickly the type of treatment required by the subject.
Claims21
1-33. (canceled)
A method for diagnosing stroke and determining the evolution of occurrence thereof comprising:
- a) analyzing a body fluid of a patient to detect the presence and concentration level of a first ischemic marker and a second ischemic marker, wherein each of said first and second ischemic markers is a specific glial marker, a specific neuronal marker or a specific axonal marker;
- b) analyzing the body fluid of said patient to detect the presence and concentration level of a brain endothelial cell membrane protein;
- and
- c) from the information obtained from said analyses, verifying the occurrence of stroke and determining whether the stroke is evolving in severity or subsiding.
Dependencies are inferred from the claim text.