Method for identification of somatic stem cells
OwnerAnsgar J. Pommer, Lars Philipsen +5inventors
InventorsAnsgar J. Pommer, Lars Philipsen, Anja Bastian, Harald Gollnick, Bernd Bonnekoh, Walter Schubert, Raik Bõckelmann
Life of this patent
Estimating the term…
Abstract
The invention relates to a method for identification of somatic stem cells, wherein the spatial arrangement of epitopes in a sample is captured by MELC technology for identifying the phenotype specific to the somatic stem cells. The invention moreover relates to a composition, a kit and a biochip comprising at least one antibody and/or ligand which can be employed for the performance of the method.
Claims18
Method for identification of somatic stem cells, wherein the spatial arrangement of epitopes in a sample is captured by MELC technology for identifying the phenotype specific to the somatic stem cells.
Composition or kit comprising at least one antibody and/or at least one ligand binding the epitopes Ki67, CD71, pan cytokeratin, CD29, CD49d specifically and being coupled each with in particular different labelings.
Biochip for the detection of keratinocyte stem cells, wherein on one surface of the chip at least one ligand and/or at least one antibody binding specifically to the specific phenotype “Ki67 off/CD71 off/pan cytokeratin on/CD29 on/CD49d on” are coupled in such a way that their bondability to the phenotype is sustained.
Use of the MELC robot technology for in-situ identification of somatic stem cells.
Dependencies are inferred from the claim text.