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US 2010/0136580 A1Published application
Disheveled pdz modulators
AssigneeGenentech, Inc.
InventorsYingnan Zhang, Mike Costa, Sachdev S. Sidhu
Life of this patent
Estimating the term…
Abstract
The invention provides modulators of Dvl PDZ-ligand interaction, and methods of identifying and using these modulators.
Claims17
1-25. (canceled)
An isolated polypeptide that binds specifically to Dvl PDZ, wherein the polypeptide comprises the amino acid sequence X1-X2-W-X3-D-X4-P, and wherein X1 is L or V, X2 is L, X3 is S or T, and X4 is I, F or L.
A polypeptide consisting essentially of the amino acid sequence of SEQ ID NO:
- 176.
Dependencies are inferred from the claim text.