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US 2010/0136566 A1Published application
Lateral flow strip assay with immobilized conjugate
AssigneeAbaxis, Inc.
InventorsRajesh K. MEHRA, Kenneth P. ARON
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Abstract
The present invention discloses analyte detection devices for detecting one or more analytes present in test samples, especially biological samples. In particular, the devices of the invention are lateral flow assay devices comprising immobilized metal nanoparticle conjugates as the detection means. Methods of using the devices and kits comprising the devices are also described.
Claims42
An analyte detection device comprising
- a detecting complex immobilized on a first surface,
- wherein the detecting complex comprises a first binding partner coupled to a detectable entity,
- wherein the first binding partner is capable of forming a complex with a target analyte, and
- wherein the detecting complex is formed prior to being immobilized on the first surface.
1 more element
An analyte detection device comprising
- a first detecting complex and a second detecting complex immobilized on at least one surface,
- wherein the first detecting complex comprises a first binding partner coupled to a first detectable entity,
- wherein the second detecting complex comprises a second binding partner coupled to a second detectable entity,
- wherein the first binding partner is capable of forming a complex with a first target analyte and the second binding partner is capable of forming a complex with a second target analyte, and
- wherein the first detecting complex and the second detecting complex are formed prior to being immobilized on the at least one surface.
2 more elements
Dependencies are inferred from the claim text.