Medicaments
AssigneeInnovata Biomed Limited
InventorMark Sanders
Life of this patent
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Abstract
There is described a bimodal pharmaceutical composition comprising effective amounts of a first active ingredient which substantially comprises a coarse fraction and a second active ingredient which substantially comprise a fine fraction characterized in that the coarse fraction possesses a greater mass median aerodynamic diameter than the fine fraction. There is also described a method of delivering a therapeutically effective amount of a substantially fine active ingredient to the lung of a patient by co-administration with a substantially coarse active ingredient.
Claims52
A bimodal pharmaceutical composition comprising:
- effective amounts of a first active ingredient which substantially comprises a coarse fraction;
- and
- a second active ingredient which substantially comprises a fine fraction;
- characterised in that the coarse fraction possesses a greater mass median aerodynamic diameter (MMAD) than the fine fraction.
A dry powder inhaler containing a pharmaceutical composition comprising:
- effective amounts of a first active ingredient which substantially comprises a coarse fraction;
- and
- a second active ingredient which substantially comprises a fine fraction;
- which fractions may be administered simultaneously, sequentially or separately.
A method of delivering a therapeutically effective amount of a substantially fine active ingredient to the lung of a patient by the co-administration with a substantially coarse active ingredient.
A method of treating a respiratory disorder which comprises the simultaneous, sequential or separate administering of a therapeutically effective amount of a substantially coarse fraction of an anti-inflammatory agent and a substantially fine fraction of a bronchodilator to a patient suffering from such a disorder.
A method of treating COPD which comprises the simultaneous, sequential or separate administering of a therapeutically effective amount of a substantially fine fraction of a corticosteroid and a substantially coarse fraction of a bronchodilator to a patient suffering from such a disorder.
Dependencies are inferred from the claim text.